• Renal disorders
    • Glomerulonephritis- increased LDL
    • Protein losing nephropathies- increased LDL
    • Chronic kidney disease- increased triglycerides
    • Immunosuppression (after renal transplant)- increased triglycerides
  • Hormonal causes
    • Hypothyroidism- increased LDL and triglycerides
    • Estrogens- increased triglycerides and HDL, decreased LDL
    • Pregnancy- increased triglycerides
    • Male sex hormones- decreased triglycerides
    • Growth hormone- increased HDL, decreased LDL
  • Metabolic causes-
    • Metabolic syndrome- increased triglycerides, decreased HDL
    • Diabetes- increased triglycerides, decreased HDL
    • Glycogen storage diseases- increased triglycerides
  • Liver diseases-
    • Obstructive jaundice- increased lipoprotein X- LDL like particle with very low cholesterol esters- xanthomas in face and palms
  • Drugs-
    • Increased triglycerides-
      • Thiazides
      • Non-selective beta-blockers
      • Retinoic acid
      • Estrogen
      • Steroids
      • Other immunosuppressives